The effect of moderate consumption of non-nutritive sweeteners on glucose tolerance and body composition in rats
Applied Physiology, Nutrition, and Metabolism, 2017•cdnsciencepub.com
Glucose tolerance and body composition were determined in male rats given non-nutritive
sweeteners (NNS)(aspartame or sucralose) in drinking water. Areas under the curve for
glucose and insulin with NNS did not differ from control. NNS treatment had no effect on
weight gain or percent body fat. Epididymal fat pad mass was higher with aspartame and the
ratio of trunk to total fat was less with sucralose versus control, suggesting that NNS
consumption altered body fat distribution.
sweeteners (NNS)(aspartame or sucralose) in drinking water. Areas under the curve for
glucose and insulin with NNS did not differ from control. NNS treatment had no effect on
weight gain or percent body fat. Epididymal fat pad mass was higher with aspartame and the
ratio of trunk to total fat was less with sucralose versus control, suggesting that NNS
consumption altered body fat distribution.
Glucose tolerance and body composition were determined in male rats given non-nutritive sweeteners (NNS) (aspartame or sucralose) in drinking water. Areas under the curve for glucose and insulin with NNS did not differ from control. NNS treatment had no effect on weight gain or percent body fat. Epididymal fat pad mass was higher with aspartame and the ratio of trunk to total fat was less with sucralose versus control, suggesting that NNS consumption altered body fat distribution.
Canadian Science Publishing