Subretinal transplantation of MACS purified photoreceptor precursor cells into the adult mouse retina

D Eberle, T Santos-Ferreira, S Grahl, M Ader - JoVE (Journal of Visualized …, 2014 - jove.com
Vision impairment and blindness due to the loss of the light-sensing cells of the retina, ie
photoreceptors, represents the main reason for disability in industrialized countries.
Replacement of degenerated photoreceptors by cell transplantation represents a possible
treatment option in future clinical applications. Indeed, recent preclinical studies
demonstrated that immature photoreceptors, isolated from the neonatal mouse retina at
postnatal day 4, have the potential to integrate into the adult mouse retina following …