Induction and analysis of nephrotoxic serum nephritis in mice
JM Hoppe, V Vielhauer - Innate DNA and RNA Recognition: Methods and …, 2014 - Springer
JM Hoppe, V Vielhauer
Innate DNA and RNA Recognition: Methods and Protocols, 2014•SpringerThe nephrotoxic serum nephritis (NTN) model is an integral part of experimental
glomerulonephritis (GN) research. Here, we discuss how the murine NTN model can be
induced and effectively used to mimic an immune complex-mediated GN. Further, we
differentiate between heterologous and autologous models by comparing pathophysiology
and phenotypic manifestations.
glomerulonephritis (GN) research. Here, we discuss how the murine NTN model can be
induced and effectively used to mimic an immune complex-mediated GN. Further, we
differentiate between heterologous and autologous models by comparing pathophysiology
and phenotypic manifestations.
Abstract
The nephrotoxic serum nephritis (NTN) model is an integral part of experimental glomerulonephritis (GN) research. Here, we discuss how the murine NTN model can be induced and effectively used to mimic an immune complex-mediated GN. Further, we differentiate between heterologous and autologous models by comparing pathophysiology and phenotypic manifestations.
Springer
