Self-reported ancestry, genetically determined ancestry, and APOL1 polymorphisms are
associated with variation in kidney function and related disease risk, but the relative
importance of these factors remains unclear. We estimated the global proportion of African
ancestry for 9048 individuals at Mount Sinai Medical Center in Manhattan (3189 African
Americans, 1721 European Americans, and 4138 Hispanic/Latino Americans by self-report)
using genome-wide genotype data. CKD-EPI eGFR and genotypes of three APOL1 coding …