Background In kidney transplant recipients, surveillance biopsies can reveal, despite stable
graft function, histologic features of acute rejection and borderline changes that are
associated with undesirable graft outcomes. Noninvasive biomarkers of subclinical acute
rejection are needed to avoid the risks and costs associated with repeated biopsies.
Methods We examined subclinical histologic and functional changes in kidney transplant
recipients from the prospective Genomics of Chronic Allograft Rejection (GoCAR) study who …