[HTML][HTML] AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin
The FA composition of phospholipids must be tightly regulated to maintain optimal cell
membrane properties and compensate for a highly variable supply of dietary FAs. Previous
studies have shown that AdipoR2 and its homologue PAQR-2 are important regulators of
phospholipid FA composition in HEK293 cells and Caenorhabditis elegans, respectively.
Here we show that both AdipoR1 and AdipoR2 are essential for sustaining desaturase
expression and high levels of unsaturated FAs in membrane phospholipids of many human …
membrane properties and compensate for a highly variable supply of dietary FAs. Previous
studies have shown that AdipoR2 and its homologue PAQR-2 are important regulators of
phospholipid FA composition in HEK293 cells and Caenorhabditis elegans, respectively.
Here we show that both AdipoR1 and AdipoR2 are essential for sustaining desaturase
expression and high levels of unsaturated FAs in membrane phospholipids of many human …
