Unique challenges exist in the diagnosis and treatment of glomerular diseases with their
onset during childhood. Mounting evidence supports the notion that earlier onset cases
occur due to larger numbers of genetic risk alleles. Nearly all causes of adult-onset
glomerulonephritis, nephrotic syndrome, and thrombotic microangiopathy have also been
described in children, although the prevalence of specific causes differs. Postinfectious
glomerulonephritis, Henoch-Schönlein purpura nephritis, and minimal change disease …