Mitochondrial cytopathies include a heterogeneous group of diseases that are characterized
by impaired oxidative phosphorylation. Current evidence suggests that renal involvement is
probably more frequent than originally suspected but remains subclinical in a significant
number of patients or is underestimated due to the severity of other clinical manifestations.
Until recently, these diseases were thought to develop primarily in pediatric patients but
patients that become symptomatic only in adulthood are now well recognized. From a renal …