Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV
S Bjerrum, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Cochrane Database of Systematic Reviews, 2019•cochranelibrary.com
Background The lateral flow urine lipoarabinomannan (LF‐LAM) assay Alere Determine™
TB LAM Ag is recommended by the World Health Organization (WHO) to help detect active
tuberculosis in HIV‐positive people with severe HIV disease. This review update asks the
question," does new evidence justify the use of LF‐LAM in a broader group of people?”, and
is part of the WHO process for updating guidance on the use of LF‐LAM. Objectives To
assess the accuracy of LF‐LAM for the diagnosis of active tuberculosis among HIV‐positive …
TB LAM Ag is recommended by the World Health Organization (WHO) to help detect active
tuberculosis in HIV‐positive people with severe HIV disease. This review update asks the
question," does new evidence justify the use of LF‐LAM in a broader group of people?”, and
is part of the WHO process for updating guidance on the use of LF‐LAM. Objectives To
assess the accuracy of LF‐LAM for the diagnosis of active tuberculosis among HIV‐positive …
Background
The lateral flow urine lipoarabinomannan (LF‐LAM) assay Alere Determine™ TB LAM Ag is recommended by the World Health Organization (WHO) to help detect active tuberculosis in HIV‐positive people with severe HIV disease. This review update asks the question," does new evidence justify the use of LF‐LAM in a broader group of people?”, and is part of the WHO process for updating guidance on the use of LF‐LAM.
Objectives
To assess the accuracy of LF‐LAM for the diagnosis of active tuberculosis among HIV‐positive adults with signs and symptoms of tuberculosis (symptomatic participants) and among HIV‐positive adults irrespective of signs and symptoms of tuberculosis (unselected participants not assessed for tuberculosis signs and symptoms).
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