Background: Macrophages and neutrophils are key phagocytes in regeneration. Results:
Neutrophils are the primary phagocytes in the inflammatory stage and are dispensable for
zebrafish fin regeneration, whereas macrophages mainly function in the resolution stage
and are required for fin regeneration. Conclusion: Macrophages and neutrophils behave
differently during zebrafish fin injury and regeneration. Significance: Our study documents
that macrophages and neutrophils play distinct functions in tissue regeneration.