[HTML][HTML] Regulation of hepatic gene expression by saturated fatty acids

T Vallim, AM Salter - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2010 - Elsevier
Diets rich in saturated fatty acids have long been associated with increased plasma
cholesterol concentrations and hence increased risk of cardiovascular disease. More
recently, they have also been suggested to promote the development of non-alcoholic fatty
liver disease. While there is now considerable evidence to suggest that polyunsaturated fatty
acids exert many of their effects through regulating the activity of transcription factors,
including peroxisome proliferator activated receptors, sterol regulatory binding proteins …