KK mouse
H Ikeda - Diabetes research and clinical practice, 1994 - Elsevier
H Ikeda
Diabetes research and clinical practice, 1994•ElsevierThe KK mouse strain shows inherently glucose intolerance and insulin resistance. When KK
mice become obese by aging, dietary means or other ways, such a chemical diabetic state is
changed to overt diabetic state associated with frank hyperglycemia and glucosuria.
Therefore, the KK mouse is a good model for investigating a process of expression of
obesity-associated diabetes.
mice become obese by aging, dietary means or other ways, such a chemical diabetic state is
changed to overt diabetic state associated with frank hyperglycemia and glucosuria.
Therefore, the KK mouse is a good model for investigating a process of expression of
obesity-associated diabetes.
Abstract
The KK mouse strain shows inherently glucose intolerance and insulin resistance. When KK mice become obese by aging, dietary means or other ways, such a chemical diabetic state is changed to overt diabetic state associated with frank hyperglycemia and glucosuria. Therefore, the KK mouse is a good model for investigating a process of expression of obesity-associated diabetes.
Elsevier