Albumin as fatty acid transporter

GJ van der Vusse - Drug metabolism and pharmacokinetics, 2009 - Elsevier
Fatty acids play critical roles in mammalian energy metabolism. Moreover, they are
important substrates for the synthesis of membrane phospholipids and biologically active
compounds like eicosanoids and leukotrienes. Because of their low solubility in aqueous
solutions such as blood plasma and interstitial fluid, fatty acids are in need of binding
proteins to increase their concentration in vascular and interstitial compartments. Albumin
acts as main fatty acid binding protein in extracellular fluids. Plasma albumin possesses …