Food restriction enhances oxidative status in aging rats with neuroprotective effects on myenteric neuron populations in the proximal colon
JPF Schoffen, APS Rampazzo, CP Cirilo… - Experimental …, 2014 - Elsevier
Food restriction may slow the aging process by increasing the levels of antioxidant defenses
and reducing cell death. We evaluated the effects of food restriction on oxidative and
nutritional status, myenteric cell populations, and the colonic muscle layer in aging rats.
Wistar rats were distributed into control groups (7, 12, and 23 months of age) and subjected
to food restriction (50% of normal diet) beginning at 7 months of age. The animals were
sacrificed, and blood was collected to evaluate its components and markers of oxidative …
and reducing cell death. We evaluated the effects of food restriction on oxidative and
nutritional status, myenteric cell populations, and the colonic muscle layer in aging rats.
Wistar rats were distributed into control groups (7, 12, and 23 months of age) and subjected
to food restriction (50% of normal diet) beginning at 7 months of age. The animals were
sacrificed, and blood was collected to evaluate its components and markers of oxidative …