Slow-transit constipation is usually considered a colonic motor disorder. However, there is
some evidence that abnormalities may be present in locations other than the colon. In
particular, several studies have reported abnormal motor activity of the small bowel in these
patients. We evaluated the neuropathological aspects of the terminal ileum in patients with
slow-transit constipation to see whether abnormalities are present that may explain an
abnormal motility of the small intestine. Specimens of the terminal ileum were obtained from …