COMBINED ANTI-VASCULAR CELL ADHESION MOLECULE-1 AND ANTI-LEUKOCYTE FUNCTION-ASSOCIATED MOLECULE-1 MONOCLONAL ANTIBODY …
WL Grooby, R Krishnan, JK Johnston, MM Rao… - …, 1998 - journals.lww.com
WL Grooby, R Krishnan, JK Johnston, MM Rao, GR Russ
Transplantation, 1998•journals.lww.comThis study investigates the therapeutic efficacy of an anti-vascular cell adhesion molecule
(VCAM)-1 monoclonal antibody (mAb), alone or in combination with an anti-leukocyte
function-associated-1 mAb, in prolonging allograft survival in an ovine model of renal
transplantation. The kinetics of VCAM-1 induction and expression during renal allograft
rejection have also been studied.
(VCAM)-1 monoclonal antibody (mAb), alone or in combination with an anti-leukocyte
function-associated-1 mAb, in prolonging allograft survival in an ovine model of renal
transplantation. The kinetics of VCAM-1 induction and expression during renal allograft
rejection have also been studied.
Abstract
This study investigates the therapeutic efficacy of an anti-vascular cell adhesion molecule (VCAM)-1 monoclonal antibody (mAb), alone or in combination with an anti-leukocyte function-associated-1 mAb, in prolonging allograft survival in an ovine model of renal transplantation. The kinetics of VCAM-1 induction and expression during renal allograft rejection have also been studied.
Lippincott Williams & Wilkins