Progression of fibrosis in hepatitis C with and without schistosomiasis: correlation with serum markers of fibrosis

SM Kamal, B Turner, Q He, J Rasenack, L Bianchi… - Hepatology, 2006 - journals.lww.com
Serial liver biopsies are the gold standard by which the progression of fibrosis is evaluated.
This longitudinal cohort study assessed the different rates in the progression of fibrosis using
serial liver biopsies and serum fibrosis markers YKL-40 and PIIINP and the cytokines,
transforming growth factor beta (TGF-) and tumor necrosis factor alpha (TF). A 10-year
cohort study was performed in patients with hepatitis C virus (HCV) alone or HCV and
schistosomiasis. Patients were enrolled at the time of acute HCV infection and prospectively …