[HTML][HTML] Pulmonary fibrosis: pathogenesis, etiology and regulation

MS Wilson, TA Wynn - Mucosal immunology, 2009 - Elsevier
Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied,
with an array of triggers including allergens, chemicals, radiation and environmental
particles. However, the cause of one of the most common pulmonary fibrotic conditions,
idiopathic pulmonary fibrosis (IPF), is still unclear. This review examines common
mechanisms of pulmonary wound-healing responses following lung injury, and highlights …