Liver failure and cirrhosis occur as a result of a variety of chronic hepatic injuries. They
display sequential and overlapping severe pathogenic processes that include severe
inflammation, hepatocyte necrosis, and fibrosis/cirrhosis, and carry a high mortality rate [1].
There is a prevailing contradiction between the urgent need for liver transplants and a
severe shortage of donor livers, which highlights the need to develop new therapeutic
strategies for these conditions. Recent studies have shown that stem cell-based therapies …