Hepatocellular carcinoma (HCC) is a highly prevalent and lethal neoplasia, the
management of which has significantly improved during the last few years. A better
knowledge of the natural history of the tumor and the development of staging systems that
stratify patients according to the characteristics of the tumor, the liver disease, and the
performance status, such as the BCLC (Barcelona Clinic Liver Cancer) system, have led to a
better prediction of prognosis and to a most appropriate treatment approach. Today curative …