[HTML][HTML] Vitamin D receptor protein expression in tumor tissue and prostate cancer progression
WK Hendrickson, R Flavin, JL Kasperzyk… - Journal of clinical …, 2011 - ncbi.nlm.nih.gov
Journal of clinical oncology, 2011•ncbi.nlm.nih.gov
Purpose Data suggest that circulating 25-hydroxyvitamin D [25 (OH) D] interacts with the
vitamin D receptor (VDR) to decrease proliferation and increase apoptosis for some
malignancies, although evidence for prostate cancer is less clear. How VDR expression in
tumor tissue may influence prostate cancer progression has not been evaluated in large
studies.
vitamin D receptor (VDR) to decrease proliferation and increase apoptosis for some
malignancies, although evidence for prostate cancer is less clear. How VDR expression in
tumor tissue may influence prostate cancer progression has not been evaluated in large
studies.
Abstract
Purpose
Data suggest that circulating 25-hydroxyvitamin D [25 (OH) D] interacts with the vitamin D receptor (VDR) to decrease proliferation and increase apoptosis for some malignancies, although evidence for prostate cancer is less clear. How VDR expression in tumor tissue may influence prostate cancer progression has not been evaluated in large studies.
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