Allelic imbalance of 14q32 in esophageal carcinoma
Y Ihara, Y Kato, T Bando, F Yamagishi… - Cancer genetics and …, 2002 - Elsevier
It has been demonstrated that the accumulation of alterations in several oncogenes and
tumor suppressor genes plays a role in the initiation and progression of esophageal
carcinoma. However, to our knowledge, very few studies have described the molecular
genetic changes of chromosome arm 14q in esophageal carcinoma. In this study, we
examined 35 primary esophageal carcinomas for allelic imbalance on 14q32. Analysis of
four polymorphic microsatellite markers identified 13 (37%) tumors exhibiting allelic …
tumor suppressor genes plays a role in the initiation and progression of esophageal
carcinoma. However, to our knowledge, very few studies have described the molecular
genetic changes of chromosome arm 14q in esophageal carcinoma. In this study, we
examined 35 primary esophageal carcinomas for allelic imbalance on 14q32. Analysis of
four polymorphic microsatellite markers identified 13 (37%) tumors exhibiting allelic …