Effect of lipid-derived second messengers on electrophysiological taste responses in the gerbil
SS Schiffman, MS Suggs, ML Losee, LA Gatlin… - Pharmacology …, 1995 - Elsevier
Integrated chorda tympani (CT) recordings were made to salty, sour, sweet, bitter, and
glutamate tastants before and after a 4-min application of modulators of lipid-derived second
messenger systems. The modulators included two membrane-permeable analogues of
DAG, 1-oleoyl-2-acetyl glycerol (OAG) and dioctanoyl glycerol (DiC8); thapsigargin, which
releases Ca++ from intracellular stores; ionomycin, a calcium ionophore; lanthanum
chloride, an inorganic calcium channel blocker; nifedipine, a dihydropyridine calcium …
glutamate tastants before and after a 4-min application of modulators of lipid-derived second
messenger systems. The modulators included two membrane-permeable analogues of
DAG, 1-oleoyl-2-acetyl glycerol (OAG) and dioctanoyl glycerol (DiC8); thapsigargin, which
releases Ca++ from intracellular stores; ionomycin, a calcium ionophore; lanthanum
chloride, an inorganic calcium channel blocker; nifedipine, a dihydropyridine calcium …
