Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons
M Koike, M Iino, S Ozawa - Neuroscience research, 1997 - Elsevier
Effects of 1-naphthyl acetyl spermine (NASPM), a synthetic analogue of Joro spider toxin
(JSTX), on α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate
receptors were studied in cultured rat hippocampal neurons using the whole-cell patch
clamp technique. A population of cultured neurons had AMPA receptors with a strong inward
rectification and a high permeability to Ca2+ (type II neurons), whereas most neurons (type I
neurons) had AMPA receptors with a slight outward rectification and little Ca2+ permeability …
(JSTX), on α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate
receptors were studied in cultured rat hippocampal neurons using the whole-cell patch
clamp technique. A population of cultured neurons had AMPA receptors with a strong inward
rectification and a high permeability to Ca2+ (type II neurons), whereas most neurons (type I
neurons) had AMPA receptors with a slight outward rectification and little Ca2+ permeability …
