Effects of dietary fructose on plasma glucose and hormone responses in normal and hyperinsulinemic men

J Hallfrisch, KC Ellwood, OE Michaelis IV, S Reiser… - The Journal of …, 1983 - Elsevier
Twelve men with abnormally high insulin responses to a sucrose load and 12 normal men
were fed diets containing 0, 7.5, or 15% of the calories as fructose for 5 weeks each. The
diets contained approximately 43% of the calories as total carbohydrate, 42% as fat and
15% as protein. Mean insulin responses of the hyperinsulinemic men were initially 235% of
control responses. Plasma glucose concentrations 1 hour after the sucrose load were
significantly higher in hyperinsulinemic men than in controls. There were no initial …