Increased plasmin‐α2‐antiplasmin levels indicate activation of the fibrinolytic system in systemic amyloidoses

B Bouma, C Maas, BPC Hazenberg… - Journal of Thrombosis …, 2007 - jthjournal.org
Systemic amyloidosis is marked by accumulation of amyloid deposits in various tissues
throughout the body. In most cases, impairment of organ function by these deposits leads to
morbid and complex pathological conditions. Primary systemic amyloidosis (AL) is caused
by accumulation of monoclonal immunoglobulin light-chains (LC), which are overproduced
by plasma cells [1]. AL is the most prevalent form of systemic amyloidosis. Secondary
systemic amyloidosis (AA) can be recognized by the accumulation of serum amyloid A …