Diuretic effects on calcium metabolism.

PA Friedman, DA Bushinsky - Seminars in nephrology, 1999 - europepmc.org
PA Friedman, DA Bushinsky
Seminars in nephrology, 1999europepmc.org
Diuretics have numerous effects on calcium metabolism. The loop diuretics promote, and the
thiazide diuretics inhibit, renal calcium excretion. In this review we detail the basic
mechanisms of renal calcium excretion and then explain how diuretics influence this
excretion. Finally we review how these agents can be used to alter calcium homeostasis in a
clinically efficacious manner.
Diuretics have numerous effects on calcium metabolism. The loop diuretics promote, and the thiazide diuretics inhibit, renal calcium excretion. In this review we detail the basic mechanisms of renal calcium excretion and then explain how diuretics influence this excretion. Finally we review how these agents can be used to alter calcium homeostasis in a clinically efficacious manner.
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