The successful use of protein C concentrate during pregnancy in a patient with type 1 protein C deficiency, previous thrombosis and recurrent fetal loss
EM Richards, M Makris… - British journal of …, 1997 - Wiley Online Library
EM Richards, M Makris, FE Preston
British journal of haematology, 1997•Wiley Online LibraryThe risks of venous thrombosis and fetal loss are increased in patients with protein C
deficiency. We describe a patient with a history of thrombosis and recurrent fetal loss who
was found to have type 1 protein C deficiency. In view of her history and intolerance of
heparin preparations, she was treated with protein C concentrate during the first and third
trimesters of her seventh pregnancy. The patient suffered no thromboembolic event during
this pregnancy and gave birth to a healthy infant. The implications of the success of this …
deficiency. We describe a patient with a history of thrombosis and recurrent fetal loss who
was found to have type 1 protein C deficiency. In view of her history and intolerance of
heparin preparations, she was treated with protein C concentrate during the first and third
trimesters of her seventh pregnancy. The patient suffered no thromboembolic event during
this pregnancy and gave birth to a healthy infant. The implications of the success of this …
The risks of venous thrombosis and fetal loss are increased in patients with protein C deficiency. We describe a patient with a history of thrombosis and recurrent fetal loss who was found to have type 1 protein C deficiency. In view of her history and intolerance of heparin preparations, she was treated with protein C concentrate during the first and third trimesters of her seventh pregnancy. The patient suffered no thromboembolic event during this pregnancy and gave birth to a healthy infant. The implications of the success of this therapeutic strategy are discussed.
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