Parkinson disease in twins: an etiologic study
CM Tanner, R Ottman, SM Goldman, J Ellenberg… - Jama, 1999 - jamanetwork.com
ContextThe cause of Parkinson disease (PD) is unknown. Genetic linkages have been
identified in families with PD, but whether most PD is inherited has not been determined.
ObjectiveTo assess genetic inheritance of PD by studying monozygotic (MZ) and dizygotic
(DZ) twin pairs. DesignTwin study comparing concordance rates of PD in MZ and DZ twin
pairs. Setting and ParticipantsA total of 19,842 white male twins enrolled in the National
Academy of Sciences/National Research Council World War II Veteran Twins Registry were …
identified in families with PD, but whether most PD is inherited has not been determined.
ObjectiveTo assess genetic inheritance of PD by studying monozygotic (MZ) and dizygotic
(DZ) twin pairs. DesignTwin study comparing concordance rates of PD in MZ and DZ twin
pairs. Setting and ParticipantsA total of 19,842 white male twins enrolled in the National
Academy of Sciences/National Research Council World War II Veteran Twins Registry were …