Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and …
RS Devon, S Anderson, PW Teague… - Psychiatric …, 2001 - journals.lww.com
We have undertaken a search for polymorphic sequence variation within Disrupted in
Schizophrenia 1 and Disrupted in Schizophrenia 2 (DISC1 and DISC2), which are both
novel genes that span a translocation breakpoint strongly associated with schizophrenia
and related psychoses in a large Scottish family. A scan of the coding sequence, intron/exon
boundaries, and part of the 5′ and 3′ untranslated regions of DISC1, plus 2.7 kb at the
3′ end of DISC2, has revealed a novel microsatellite and 15 novel single nucleotide …
Schizophrenia 1 and Disrupted in Schizophrenia 2 (DISC1 and DISC2), which are both
novel genes that span a translocation breakpoint strongly associated with schizophrenia
and related psychoses in a large Scottish family. A scan of the coding sequence, intron/exon
boundaries, and part of the 5′ and 3′ untranslated regions of DISC1, plus 2.7 kb at the
3′ end of DISC2, has revealed a novel microsatellite and 15 novel single nucleotide …
