Epstein-Barr virus and multiple sclerosis

A Ascherio, M Munch - Epidemiology, 2000 - journals.lww.com
It has been suggested that the Epstein-Barr virus (EBV) plays a role in the etiology of
multiple sclerosis (MS), but individual epidemiologic studies have been inconclusive, in part
because of the high prevalence of previous infection among individuals without MS. We
conducted a systematic review of case-control studies comparing EBV serology in MS
patients and controls. Eight published investigations were identified, including a total of
1,005 cases and 1,060 controls. The summary odds ratio of MS comparing EBV seropositive …