[HTML][HTML] Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase
Amine oxidations are important in a number of basic biological processes ranging from lysyl
oxidation in the cross-linking of collagen to the degradative metabolism of polyamines and
neurotransmitters. The oxidations of biogenic amines to the corresponding imines are
catalyzed by either the quinoprotein class of enzymes (usually primary amines)(1) or by the
flavin-containing amine oxidases (primary, secondary, or tertiary amines)(2). In both cases,
molecular oxygen is the usual electron acceptor with hydrogen peroxide formed as reaction …
oxidation in the cross-linking of collagen to the degradative metabolism of polyamines and
neurotransmitters. The oxidations of biogenic amines to the corresponding imines are
catalyzed by either the quinoprotein class of enzymes (usually primary amines)(1) or by the
flavin-containing amine oxidases (primary, secondary, or tertiary amines)(2). In both cases,
molecular oxygen is the usual electron acceptor with hydrogen peroxide formed as reaction …
