[CITATION][C] An intestinal receptor for heme: its partial characterization
R Tenhunen, R Gräsbeck, I Kouvonen… - International Journal of …, 1980 - Elsevier
1. An intestinal macromolecular heme∗ binder both from human and porcine intestinal
brush borders has been solubilized and partly purified. 2. 2. This heme binder is not
albumin, hemopexin, glutathione-S-transferase or aggregated heme. Heme, but not intact
hemoglobin seems to be bound to this binder. A 100-fold molar excess of FeSO 4 does not
inhibit the uptake of heme by this binder. 3. 3. The dissociation constant of the binder-heme
complex is 10− 6 to 10− 7 mol/l thus justifying the term heme receptor. 4. 4. Presumably a …
brush borders has been solubilized and partly purified. 2. 2. This heme binder is not
albumin, hemopexin, glutathione-S-transferase or aggregated heme. Heme, but not intact
hemoglobin seems to be bound to this binder. A 100-fold molar excess of FeSO 4 does not
inhibit the uptake of heme by this binder. 3. 3. The dissociation constant of the binder-heme
complex is 10− 6 to 10− 7 mol/l thus justifying the term heme receptor. 4. 4. Presumably a …
