Prostaglandin-induced hyperostosis: a case report
DM DRVARIC, WJ PARKS, JB WYLY… - Clinical Orthopaedics …, 1989 - journals.lww.com
The use of prostaglandin-E 1,(PGE 1) to maintain patency of the ductus arteriosus in infants
with ductal-dependent congenital heart disease is now well established. A 2.5-month-old
child with cyanotic heart disease who required long-term PGE, infusions, developed
widespread periosteal reactions during the course of therapy. Prostaglandin-induced
subperiosteal hyperostosis should now be considered in the differential diagnosis of
neonatal cortical proliferation.
with ductal-dependent congenital heart disease is now well established. A 2.5-month-old
child with cyanotic heart disease who required long-term PGE, infusions, developed
widespread periosteal reactions during the course of therapy. Prostaglandin-induced
subperiosteal hyperostosis should now be considered in the differential diagnosis of
neonatal cortical proliferation.
