Context.—Lysophosphatidic acid (LPA) has been shown to stimulate proliferation of ovarian
cancer cells and is present in the ascitic fluid of patients with ovarian cancer. Objectives.—
To determine whether elevated levels of LPA are present in plasma from patients with
ovarian cancer and other gynecologic malignancies compared with healthy controls and to
evaluate whether an elevated LPA plasma level may be a biomarker for these diseases.
Design.—A research assay was used to measure total LPA levels in plasma from healthy …