Close association of Guillain–Barré syndrome with antibodies to minor monosialogangliosides GM1b and GM1α

N Yuki, Y Tagawa, F Irie, Y Hirabayashi… - Journal of …, 1997 - Elsevier
Cumulative evidence supports the theory that anti-ganglioside antibodies function in the
development of Guillain–Barré syndrome (GBS). Some patients have developed GBS after
the administration of monosialoganglioside extracted from bovine brain. To clarify the
pathogenesis of GBS associated with and without administration of the
monosialoganglioside fraction, we investigated serum antibodies to the minor
monosialogangliosides GM1b and GM1α in patients with GBS and in control patients. GM1b …