Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus
A Kondratyev, N Sahibzada, K Gale - Molecular brain research, 2001 - Elsevier
In the aftermath of prolonged continuous seizure activity (status epilepticus, SE), neuronal
cell death occurs in the brain regions through which the seizure propagates. The
vulnerability to adrenalectomy-induced apoptotic neuronal death was recently reported to be
reduced by prior exposure to repeated daily noninjurious electroconvulsive shock (ECS).
The present studies identified apoptosis and apoptosis-associated gene products in the
neurodegenerative response to experimentally controlled periods (1 or 2 h) of SE in the rat …
cell death occurs in the brain regions through which the seizure propagates. The
vulnerability to adrenalectomy-induced apoptotic neuronal death was recently reported to be
reduced by prior exposure to repeated daily noninjurious electroconvulsive shock (ECS).
The present studies identified apoptosis and apoptosis-associated gene products in the
neurodegenerative response to experimentally controlled periods (1 or 2 h) of SE in the rat …