Cross-reactivity of human molecular markers for detection of prethrombotic states in various animal species

C Ravanat, M Freund, F Dol, Y Cadroy… - Blood coagulation & …, 1995 - journals.lww.com
The aim of the present study was to investigate the reactivity of immunoreagents developed
for clinical applications in humans in different animal species (hen, mouse, rat, rabbit,
guinea-pig, dog, pig, sheep, baboon). Prothrombin fragment 1+ 2, thrombin-antithrombin III
complex and fibrinopeptide A were tested for coagulation, platelet factor 4 and [beta]-
thromboglobulin for platelet activation, glycoprotein IIb-IIIa, glycoprotein Ib and P-selectin for
platelet membrane glycoproteins, D-dimers for fibrinolysis, thrombomodulin for activation of …