Coated stents for the prevention of restenosis: Part II

MN Babapulle, MJ Eisenberg - Circulation, 2002 - Am Heart Assoc
MN Babapulle, MJ Eisenberg
Circulation, 2002Am Heart Assoc
this type of stent is very well tolerated in humans. The same group24 showed that
phosphorylcholine coated stents had low rates of subacute stent thrombosis (0%) and
restenosis (12%), even when used in the setting of primary PCI for acute myocardial
infarction. Phosphorylcholine-coated stents have also been examined in the setting of PCI of
small coronary vessels. In a retrospective series of 90 patients undergoing stenting of
vessels 2.0 to 2.8 mm in diameter, Beaudry et al25 reported a MACE rate of 20%. Similar …
this type of stent is very well tolerated in humans. The same group24 showed that phosphorylcholine coated stents had low rates of subacute stent thrombosis (0%) and restenosis (12%), even when used in the setting of primary PCI for acute myocardial infarction. Phosphorylcholine-coated stents have also been examined in the setting of PCI of small coronary vessels. In a retrospective series of 90 patients undergoing stenting of vessels 2.0 to 2.8 mm in diameter, Beaudry et al25 reported a MACE rate of 20%. Similar results have been obtained after deploying these stents in vessels 2.0 mm in diameter. 26 Unfortunately, the lack of routine follow-up angiography is the major limitation of these 5 studies, and although well tolerated, it is unclear if phosphorylcholine-coated stents inhibit neointimal hyperplasia to a significant degree (Table 2).
Am Heart Assoc