Intrathymic and extrathymic clonal deletion of T cells
J Sprent, SR Webb - Current opinion in immunology, 1995 - Elsevier
J Sprent, SR Webb
Current opinion in immunology, 1995•ElsevierClonal elimination accounts for self-tolerance induction in the thymus and also affects
mature T cells responding to exogenous antigens in the periphery. Recent evidence on the
microenvironments, cell—cell interactions and signalling requirements for clonal deletion of
immature and mature T cells is discussed.
mature T cells responding to exogenous antigens in the periphery. Recent evidence on the
microenvironments, cell—cell interactions and signalling requirements for clonal deletion of
immature and mature T cells is discussed.
Clonal elimination accounts for self-tolerance induction in the thymus and also affects mature T cells responding to exogenous antigens in the periphery. Recent evidence on the microenvironments, cell—cell interactions and signalling requirements for clonal deletion of immature and mature T cells is discussed.
Elsevier
