Beta1 integrin-mediated adhesion between renal tubular cells after anoxic injury.

W Lieberthal, JB McKenney, CR Kiefer… - Journal of the …, 1997 - journals.lww.com
Abstract beta 1 integrin-mediated adhesion between renal tubular cells after anoxic injury.
This study examined the effect of sublethal injury, induced by ATP depletion (5 mM cyanide
in the absence of dextrose), on the distribution and function of beta 1 integrins in primary
cultures of mouse proximal tubular (MPT) cells. It was shown in this study that sublethal
injury results in loss of focal contacts present in uninjured MPT cells, and that the beta 1
integrin molecule becomes redistributed to the apical membrane domain of sublethally …